Cardiovascular magnetic resonance deformation imaging: method comparison and considerations regarding reproducibility

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main source(s): German Centre for Cardiovascular Research Purpose Myocardial Feature-Tracking (FT) deformation imaging is superior risk-stratification compared to volumetric approaches. Since there no clear recommendation regarding FT post-processing, we different FT-strain analyses with reference standard techniques, including tagging and strain encoded (SENC) magnetic resonance imaging. Methods software from 4 vendors (TomTec/Medis/Circle(CVI)/Neosoft), (Segment), fastSENC (MyoStrain) were used determine left ventricular global circumferential longitudinal strains (GCS/GLS) in 12 healthy volunteers heart failure patients. Variability agreements assessed using intraclass correlation coefficients absolute agreement (ICCa) consistency (ICCc) as well pearson coefficients. Results For FT-GCS, was excellent comparing FT-vendors (ICCc = 0.84-0.97, r 0.86-0.95) fSENC 0.78-0.89, 0.73-0.81). FT-GCS 0.79-0.85, 0.74-0.77) except TomTec 0.68, 0.72). Absolute between highest CVI Medis (ICCa 0.96) lowest Neosoft 0.32). Similarly, both 0.84-0.88), good 0.77 0.64) 0.41 0.47). FT-GLS, (ICCc?0.86, r?0.76). 0.91-0.93) or 0.69-0.85). (CVI 0.70, 0.60) fair (TomTec 0.41, 0.59) but 0.77-0.90). Conclusion Although differ depending on assessment approaches, are consistently high irrespective the method chosen, thus indicating reliable assessment. Further standardisation introduction uniform references warranted routine clinical implementation.